Clostridium tetani Toxin Monoclonal Antibody
Catalog No.: 18917
Clone No.: B418M
MAb Subtype: IgG2a
Format: Purified antibody in PBS, pH 7.4.
Clostridium tetani is an anaerobic, gram-positive, spore-forming rod found in soil and in the intestinal tracts and feces of animals. Most cases of tetanus result C. tetani spores entering small puncture wound. Infections remain localized, but systemic damage results from the production of exotoxins that are released when the spores germinate and grow. Tetanus toxin “Tetanospasmin” is one of the most potent toxins known, third only to botulinum toxin and diphtheria toxin. This potent neurotoxin enters peripheral nerves and travels to the central nervous system where it interferes with the release of neurotransmitters, causing muscle contraction and spasm.
Antigen: Toxin purified from culture filtrate of C. tetani.
Host Species: Mouse
Accession nos.: P04958, NP_783831
Gene ID: 24255210
Specificity: This antibody recognizes C. tetani toxin.
Immunoblotting A band of ~150,000 is detected.
Endusers should determine optimal dilutions for their applications.
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20° to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not intended for use in therapeutic or diagnostic procedures.