Anti-CIDE-B (CT) Antibody (2091)

$445.00

Host Quantity Applications Species Reactivity Data Sheet  
Rabbit 100ug ELISA,WB Mouse
SKU: 2091 Categories: , ,
Overview
Product Name Anti-CIDE-B (CT) Antibody (2091)
Description Anti-CIDE-B (CT) Rabbit Polyclonal Antibody
Target CIDE-B (CT)
Species Reactivity Mouse
Applications ELISA,WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Immunogen Peptide corresponding to aa 204- 219 of mouse CIDE-B (accession no. AF041377).
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by peptide immuno-affinity chromatography
Specificity Information
Specificity This antibody recognizes mouse CIDE-B (25kDa) and does not cross-react with CIDE-A.
Target Name Cell death activator CIDE-B
Target ID CIDE-B (CT)
Uniprot ID O70303
Alternative Names Cell death-inducing DFFA-like effector B
Gene Name Cideb
Gene ID 12684
Accession Number NP_034024
Biological Function Activates apoptosis.
Research Areas Apoptosis
Background DFF45-related proteins CIDE-A and CIDE-B have recently been identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow.
Application Images
Description Western blot analysis of CIDE-B in mouse liver tissue lysate with CIDE-B antibody at 1:500 dilution.
Additional Information
Handling
Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.
Application Instructions Immunoblotting: use at 2ug/mL.

These are recommended concentrations.

Enduser should determine optimal concentration for their application.

Positive control: Tissue lysate of mouse liver.
References & Data Sheet