Product Name Anti-Cholera Toxin β Subunit Antibody (20201)
Description Anti-Cholera toxin β subunit Mouse Monoclonal Antibody
Target Cholera Toxin β Subunit
Species Reactivity Cholera Toxin Beta Subunit
Clone ID 3D11
Immunogen Purified beta subunit of cholera toxin.
Concentration Lot Specific
Formulation PBS containing 0.1% sodium azide
Buffer Formulation Phosphate Buffered Saline
Buffer Anti-Microbial 0.1% Sodium Azide
Purification Purified by Protein A affinity chromatography
Specificity This antibody recognizes the beta subunit of cholera toxin and does not cross-react with the alpha subunit, however it cross-reacts with E. coli heat labile enterotoxin.
Target Name Cholera enterotoxin subunit B
Target ID Cholera Toxin β Subunit
Uniprot ID P01556
Alternative Names Cholera enterotoxin B chain, Cholera enterotoxin γ chain, Choleragenoid
Gene Name ctxB
Sequence Location Secreted. Host cell membrane
Biological Function The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.
Research Areas Infectious Disease
Storage These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions This antibody may be used for detection of cholera toxin in ELISA. Not all applications have been investigated.