Chlamydia trachomatis MOMP

Chlamydia trachomatis MOMP Monoclonal Antibodies

ORDERING INFORMATION

Catalog No. 15103	Clone No. MAb Subtype CL12-666.33.3 IgG3**	Size 100ug, 500ug	Library Pack No. 100ug/clone 151111 All 11 clones
15108	CL12-671.11.23 IgG3**	100ug, 500ug
15115	CL12-674.5 IgG3**	100ug, 500ug
15125	CL12-689.2.8 IgG3**	100ug, 500ug
15128	CL12-707.21 IgG2a*	100ug, 500ug
15129	CL12-707.7 IgG2a*	100ug, 500ug
15130	CL12-712.3 IgG2a*	100ug, 500ug
15135	CL12-717.16 IgG2a*	100ug, 500ug
15140	CL12-741.24.5.5 IgG2a*	100ug, 500ug
15145	CL12-755.1.31.3 IgG3**	100ug, 500ug
15156	CL13-227.1.2 IgG2a*	100ug, 500ug

Format: *Protein G-purified antibody in PBS, pH 7.4.
**PEG-purified antibody in PBS, pH 7.4.

BACKGROUND

Chlamydia trachomatis is a gram-negative bacterium that infects the columnar epithelium of the cervix, urethra, and rectum, as well as nongenital sites such as the lungs and eyes. The bacterium is the cause of the most frequently reported sexually transmitted disease in the United States, which is responsible for more than 1 million infections annually. Most persons with this infection are asymptomatic. Untreated infection can result in serious complications such as pelvic inflammatory disease, infertility, and ectopic pregnancy in women, and epididymitis and orchitis in men.

SPECIFICATION SUMMARY

Antigen: C. trachomatis elementary bodies, L2 serovar.
Host Species: Mouse
Specificity: These antibodies recognize Chlamydia trachomatis serovars A, B, Ba, C, D, E, F, G, H, I, J, K, L1, L2, L3. MOMP specificity confirmed as follows: antibody reactivity is eliminated after treatment of EBs with proteinase K (which destroys protein but leaves carbohydrate unaltered) but is unaffected by sodium periodate treatment of EBs (which destroys LPS but leaves protein unaltered).
Endusers should determine optimal concentrations for their applications.

APPLICATIONS

These antibodies have been qualified for use in ELISA to detect Chlamydia trachomatis elementary bodies and reticulate bodies.

DILUTION INSTRUCTIONS

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE AND STABILITY

These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.

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