Ceramide Kinase Polyclonal Antibody
Catalog No.: 13805
Size: 50ug peptide immunogen affinity purified antibody in PBS containing 0.1% sodium azide.
Ceramide kinase (CERK), which phosphorylates ceramide to produce ceramide 1-phosphate (C1P), was first described as a Ca+2-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in plymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.
Antigen: Synthetic peptide conjugated to KLH.
Host Species: Rabbit
Preservatives: 0.1% sodium azide
This antibody recognizes the N-terminal extracellular domain of human CERK.
Immunohistochemistry: Use at 20ug/ml.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable at 4°C (short- term) and -70°C (long-term).
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.