Catalog No.: 2245
Size: 100ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. Caspase-13 or ERICE (Evolutionarily Related Interleukin-1 Converting Enzyme) was recently described. When activated by caspase-8, caspase-13 induces apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.
Antigen: Peptide corresponding to aa 91- 105 of human caspase-13 (accession no. O75601).
Host Species: Rabbit
Preservatives: 0.02% sodium azide.
This antibody recognizes human, mouse, and rat caspase-13 (43kDa).
Immunoblotting: use at 1ug/ml.
Immunohistochemistry: use at 10ug/ml.
These are recommended concentrations. Endusers should determine optimal concentrations for their applications.
Positive control: Whole cell lysate from HL60 cells.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.