Catalog No.: 11003
Size: 100ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Antigen: Peptide corresponding to aa 521-536 of human CARD9 (accession no. AF31187).
This sequence differs from that of rat CARD9 by two amino acids.
Host Species: Rabbit
Preservatives: 0.02% sodium azide
This antibody recognizes human CARD9, a novel CARD (Caspase Recruitment Domain)- containing protein that interacts with the CARD activation domain of Bcl-10. CARD9 associates with Bcl-10 to form a complex within cells. CARD9 induces apoptosis and activates NF- B.
Immunoblotting: use at 2-3ug/ml. A band of 59kDa is detected.
Immunocytochemistry: use at 10ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their applications.
Positive control: PC-3 cell lysate.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.