Anti-CAD (CT) Antibody
Catalog No.: 2011
Size: 100ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A mouse DNase that causes DNA fragmentation was identified recently and designated CAD (caspase activated deoxyribo- nuclease). Activation of CAD/DFF40, which causes DNA degradation, is the hallmark of apoptotic cell death.
Antigen: Peptide corresponding to aa 314-329 of mouse CAD (accession no. O54788).
Host Species: Rabbit
Preservatives: 0.02% sodium azide.
This antibody recognizes full-length mouse CAD (40kDa).
Immunoblotting: use at 1ug/ml.
Immunohistochemistry: use at 1ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their applications.
Positive control: Mouse lung or spleen tissue lysate.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.