Anti-Bim (IN) Antibody
Catalog No.: 2414
Size: 100ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
A novel BH3 domain-containing protein was recently identified and designated Bim or BOD from human, mouse, and rat. Bim/BOD interacts with diverse members in the pro- survival Bcl-2 subfamily including Bcl-2, Bcl-xL, and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
Antigen: Peptide corresponding to aa 22-40 of human Bim. The sequence is identical to that of mouse and is different by one amino acid from that of rat.
Host Species: Rabbit
Preservatives: 0.02% sodium azide.
This antibody recognizes full-length Bim (23kDa) of human, mouse, and rat.
Immunoblotting: use at 1ug/ml.
Immunocytochemistry: use a 10-20ug/ml
These are recommended concentrations. Enduser should determine optimal concentration for their application.
Positive control: Whole cell lysate of human K562 cells.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.