Anti-Bassoon Polyclonal Antibody
Catalog No.: 56495
Size: 100ug in PBS, pH 7.4 (1mg/ml). Purified by Protein G affinity chromatography.
Bassoon, a 420kDa protein, is localized at presynaptic nerve terminals and appears to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The C-terminal regions of the polyglutamine domains are of interest since abnormal amplification of this region in some human proteins, such as Huntingtin, can cause late-onset neuro- degeneration.
Antigen: Fusion protein corresponding to aa786-1041 (N-terminal) of human Bassoon (accession no. NM_003458.3).
Host Species: Rabbit
Antibody Class: Polyclonal
This antibody recognizes human, mouse, and rat Bassoon. Multiple isoforms are detected.
Immunoblotting: use at 1ug/ml.
Immunohistochemistry: use at 1-10ug/ml.
Immunofluorescence: use at 1-10ug/ml.
Positive control: Rat brain tissue lysate These are recommended concentrations; enduser should determine optimal concentrations for their applications.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid repeated freeze- thaw cycles.
For in vitro investigational use only. Not intended for diagnostic or therapeutic applications.