Ataxin-1 Monoclonal Antibody
Catalog no.: 56550 (clone S76-8)
Format: 100ug (1mg/ml) Protein G-purified antibody in PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.
Ataxin-1 is a member of the ATXN1 protein family. It is a neurodegenerative disorder protein that is believed to play a role in metabolism of RNA. A mutation of Ataxin-1 causes spinocerebellar ataxia type-1 (SCA1), a progressive neurodegenerative disease that primarily affects Purjinke cells in the brain stem and cerebellum. Ataxin-1 is ubiquitously expressed except in brain where it is limited to populations of neurons.
Antigen: Synthetic peptide corresponding to aa 164-197 (ATTPSQRSQLEAYSTLLAN- MGSLSQAPGHKVEPP) of mouse Ataxin-1. This sequence is 100% identical to rat and 88% identical to human Ataxin-1.
Accession no.: NP_001186233.1, P54254
Gene ID: 20238
Host Species: Mouse
Antibody Class: IgG2b
Specificity: This antibody recognizes human, mouse, and rat Ataxin-1.
Immunoblotting: use at 1-5ug/ml. A band of ~85kDa is detected.
Immunofluorescence: use at 10ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their application.
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE AND STABILITY
This product is stable for at least one (1) year at -20°C.
For in vitro investigational use only. Not intended for therapeutic or diagnostic procedures.