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Anti-Asymmetric Dimethyl Arginine Antibody

$498.00

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 100ug WB,IHC Asymmetric Dimethyl Arginine
SKU: 90005 Categories: , ,
Overview
Product Name Anti-Asymmetric Dimethyl Arginine Antibody (90005)
Description Anti-Asymmetric Dimethyl Arginine Mouse Monoclonal Antibody
Target Asymmetric Dimethyl Arginine
Species Reactivity Asymmetric Dimethyl Arginine
Applications WB,IHC
Host Mouse
Clonality Monoclonal
Clone ID 21C7
Isotype IgM
Immunogen Dimethyl-L-arginine
Properties
Form Lyophilized
Concentration 1.0 mg/mL
Formulation Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.
Buffer Formulation Tris Buffer
Format Purified
Purification Purified by Protein A affinity chromatography
Specificity Information
Specificity This antibody reacts with free and bound ADMA. It does not cross-react with free or bound arginine or NG- monomethyl arginine.
Target ID Asymmetric Dimethyl Arginine
Research Areas Hormones/Proteins
Background Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by- product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical involved in normal endothelial function and, by extension, cardio- vascular health. Since raised levels of ADMA appear to be associated with adverse human health consequences for cardiovascular disease, metabolic diseases, and also a wide range of diseases of the elderly, the possible lowering of ADMA levels may have important therapeutic effects.
Application Images
Additional Information
Handling
Storage Store at 2 - 8ºC. Do not Freeze.
Dilution Instructions Reconstitute lyophilized antibody using ultrapure to a final concentration no less than 100 ug/mL. Reconstitution with PBS or Tris buffer is acceptable if required. Protein carrier, biocide or cryopreservative can be added as needed. Aliquot and store at -20C for longterm storage. Dilute immediately prior to use.
Application Instructions Immunoblotting: use at 1-2ug/ml

Immunohistochemistry: use at 1-10ug/ml.

These are recommended concentrations.

End user should determine optimal concentrations for their applications.
References & Data Sheet