APRIL

APRIL Polyclonal Antibody

ORDERING INFORMATION

Catalog No.: 41001
Size: 100ug
Format: Antibody purified by affinity chromatography on peptide immunogen in PBS, 1mg/ml in PBS, 0.02% sodium azide.

BACKGROUND

APRIL (A Proliferation-Inducing Ligand) is a member of the TNF superfamily identified in human and mouse. Two receptors for APRIL have been designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its receptors BCMA and TACI are involved in autoimmunity and cancer.

DESCRIPTION

Antigen: Synthetic peptide corresponding to aa 180-230 of APRIL.
Accession No.: NP_003799
Gene ID: 8741
Host: Rabbit
Specificity: Human and mouse APRIL. Reactivity with other species has not been investigated.

APPLICATIONS

Immunoblotting: use at 1-4 ug/ml. A band of ~27kDa is detected.
Immunohistochemistry: use at 10ug/ml.

STORAGE AND STABILITY

This antibody is stable for three months at 4°C and at least one year at -20°C. Store in appropriate aliquots to avoid multiple freeze-thaw cycles.

For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.