Angiotensin Converting Enzyme

 Legionella pneumophila serogroup 1 LPS Monoclonal Antibody 

ORDERING INFORMATION 

Catalog No.: 15901 

Size/Format: 100ug (0.5mg/ml) Protein A+G-purified antibody in PBS, 0.02% sodium azide, 50% glycerol, 0.1% BSA. 

BACKGROUND 

Legionella pneumophila are Gram-negative aerobic coccobacilli isolated from natural and artificial fresh water reservoirs. The outer membrane of L. pneumophila is comprised of a unique lipopolysaccharide (LPS) which is less endotoxic than enterobacterial LPS. Serogroups of L. pneumophila are classified based on O-antigen determinants of their cell wall side chains. L. pneumophila is pathogenic for humans, and it has no known soil or animal sources. It is responsible for more than 98% of the cases of Legionnaires’ 

Disease, and about 95% of cases are due to serogroup 1. It has been isolated from numerous environmental sites as well as from human lung tissue, respiratory secretions, blood, and urine. 

SPECIFICATION SUMMARY 

Antigen: L. pneumophila serogroup 1 LPS conjugated to BSA. 

Host Species: Mouse 

Clone no.: 4CE4 

Antibody Class: IgG1 

SPECIFICITY 

This antibody recognizes LPS of L. pneumophila serogroup 1 (SG1). It 

does not react with serogroups 2-9, Legionella bozemanae, or Branhamella catarrharlis. 

APPLICATIONS 

ELISA: use at 0.1-1.0ug/ml with LPS on the solid phase at 5ug/ml. These are recommended concentrations. Endusers should determine optimal concentrations for their applications. 

DILUTION INSTRUCTIONS 

Dilute in PBS or medium that is identical to that used in the assay system. 

STORAGE AND STABILITY 

This antibody is stable for at least one (1) year if stored at -20oC. Store 

product in appropriate aliquots to avoid multiple freeze-thaw cycles. 

For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures. 

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