AIB1 Monoclonal Antibody
Catalog No.: 3331
Size: 100 ug Protein G-purified antibody in PBS, pH 7.4
Antigen: Peptide corresponding to the C-terminus of human AIB1 conjugated to keyhole limpet hemocyanin (KLH).
Host Species: Mouse
Antibody Class: IgG1/κ
Preservatives: None. Available on request.
This antibody recognizes human AIB1, a 160 kD protein and member of the SRC-1 family of nuclear receptor coactivators. AIB1 is amplified in breast tumors and pancreatic cancer cell lines. AIB1 interacts with the estrogen receptor to enhance estrogen- dependent transcriptional gene activation.
Immunoblotting: use at 1-5 ug/ml.
Positive control: MCF-7 cells.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.
Anzick, SL et al. 1997. Science 277: 965-968; Bautista, S et al. 1998. Clin Cancer Res 4: 2925- 2929; Ghadimi, BM et al. 1999; Am J Pathol 154: 525-536.
For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.