Aha1

Aha1 Monoclonal Antibody

ORDERING INFORMATION

Catalog No.: 11140 (clone 4H9-D7) Size: 100ug in PBS (1mg/ml), pH 7.4, 50% glycerol, 0.09% sodium azide.
Purified by Protein G affinity chromatography.

BACKGROUND

Aha1 is a member of the Hsp90 co- chaperone family that appears to stimulate Hsp90 ATPase activity by competing with p23 and other co- chaperones for Hsp90 binding. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoproteins (VSV-G). Aha 1 is expressed in numerous tissues including brain, heart, skeletal muscle, and kidney and is present at low levels in liver and placenta.

SPECIFICATION SUMMARY

Antigen: His-tagged recombinant human Aha1 (accession no. NP_036243.1)
Host Species: Mouse
Antibody Class: IgG1

SPECIFICITY

This antibody recognizes human and mouse Aha1 and cross-reacts with mouse Aha2.

APPLICATIONS

Immunoblotting: use at 1ug/ml. A band of ~38kDa is detected. Band can appear as high as 45kDa.
ELISA: use at 1-10ug/ml with Aha1 on the solid phase.
These are recommended concentrations; enduser should determine optimal concentrations for their applications.

DILUTION INSTRUCTIONS

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE AND STABILITY

This antibody is stable for at least one (1) year at -20°C. Avoid repeated freeze-thaw cycles.

For in vitro investigational use only. Not intended for diagnostic or therapeutic applications.

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