ADAM22 (extracellular) Monoclonal Antibody
Catalog No.: 56527 (clone S57-2)
Size: 100ug in PBS (1mg/ml), pH 7.4, 50% glycerol, 0.09% sodium azide.
Purified by Protein G affinity chromatography.
ADAM22 is a member of the ADAM gene family which bind integrin and may play a role in cell-to-cell or cell-to-matrix interations. ADAM22 is unique in that it is only observed in the nervous system and predominantly in brain. ADAM22 is attached by cytoskeletal scaffolds to the postsynaptic density and is a receptor for LGI1.
Antigen: Fusion protein corresponding to aa 444-526, the extracellular disintegrin domain, of mouse ADAM22 (accession no. Q9R1V6).
Host Species: Mouse
Antibody Class: IgG1
This antibody recognizes mouse, rat, and human (weak) ADAM22. It does not cross-react with ADAM11.
Immunoblotting: use at 1ug/ml. Predicted molecular weight is ~90kDa.
Positive control: Rat brain lysate.
These are recommended concentrations. Endusers should determine optimal concentrations for their applications.
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE AND STABILITY
This antibody is stable for at least one (1) year at -20°C. Avoid repeated freeze- thaw cycles.
For in vitro investigational use only. Not intended for diagnostic or therapeutic applications.