ADAM22 (cytoplasmic)

ADAM22 (cytoplasmic) Monoclonal Antibody

ORDERING INFORMATION

Catalog No.: 56528 (clone S46-30) Size: 100ug in PBS (1mg/ml), pH 7.4, 50% glycerol, 0.09% sodium azide.
Purified by Protein G affinity chromatography.

BACKGROUND

ADAM22 is a member of the ADAM gene family which bind integrin and may play a role in cell-to-cell or cell-to-matrix interations. ADAM22 is unique in that it is only observed in the nervous system and predominantly in brain. ADAM22 is attached by cytoskeletal scaffolds to the postsynaptic density and is a receptor for LGI1.

SPECIFICATION SUMMARY

Antigen: Fusion protein corresponding to aa 757-857, the cytoplasmic region, of mouse ADAM22 (accession no. Q9R1V6).
Host Species: Mouse
Antibody Class: IgG2b

SPECIFICITY

This antibody recognizes mouse, rat, and human (weak) ADAM22.

APPLICATIONS

Immunoblotting: use at 1ug/ml. Predicted molecular weight is ~90kDa.
Positive control: Rat brain lysate.
These are recommended concentrations. Endusers should determine optimal concentrations for their applications.

DILUTION INSTRUCTIONS

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE AND STABILITY

This antibody is stable for at least one (1) year at -20°C. Avoid repeated freeze- thaw cycles.

For in vitro investigational use only. Not intended for diagnostic or therapeutic applications.

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