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FragIT™ Spin Columns

For IgG Fragmentation into F(ab')2 and Fc Fragments

FragIT™ Spin Columns allow for easy and quick fragmentation of IgG into F(ab')2 and Fc fragments. FragIT™ Spin Columns come prefilled with FabRICATOR® enzyme immobilized on agarose. Fragmentation of IgG is typically a time-consuming process with low yields and heterogeneous fragments. In contrast, FragIT™ Spin Columns can fragment IgG in less than 30 minutes at physiological pH with high purity and yield

SDS page of human monoclonal IgG (Herceptin®) fragmented to F(ab')2 and Fc using FragIT™ microspin column.