Specificity Any 18750: G1 virus attachment glycoprotein (120 kD); virus-neutralizing. 18752: G2 envelope glycoprotein (35kD); virus-neutralizing.18754: G2 envelope glycoprotein (35 kD); virus-neutralizing.18756: rec Antibody is affinity-purified on human IgE and conjugated to fluorescein isothiocyanate (FITC). Fluorophore:antibody ratio = 4.7. Cross-reactivity with other immunoglobulins is negligible. Antibody is affinity-purified on human IgG. By immunoblotting and ELISA this antibody reacts specifically with human IgG and light chains common to other human immunoglobulins. This antibody may cros Antibody is affinity-purified on human IgM and conjugated to fluorescein isothiocyanate (FITC). Fluorophore:protein ratio = 5.8. This antibody may cross-react with IgM of other species. Antibody is affinity-purified on mouse IgA. Cross-reactivity with mouse IgM, IgG1, IgG2a, IgG2b, IgG2c, IgG3, and IgE is not detectable. Antibody is affinity-purified on mouse IgE. Cross-reactivity with other immunoglobulins is negligible. Antibody is affinity-purified on mouse IgG1. Cross-reactivity with mouse IgA, IgM, IgG2a, IgG2b, IgG2c, IgG3, and IgE is not detectable. Antibody is affinity-purified on mouse IgG2a. Cross-reactivity with other mouse immunoglobulins is <2%. This antibody may cross-react with IgG2a of other species. Antibody is affinity-purified on mouse IgG2b. Cross-reactivity with mouse IgA, IgM, IgG1, IgG2a, IgG2c, IgG3, and IgE is not detectable. Antibody is affinity-purified on mouse IgG2c. By immunoblotting and ELISA, this antibody reacts specifically with IgG2c of C57Bl/6, SJL, C57BL/10, CB20, and C57BL/6 x Balb/c mice. Cross-reactivity wi Antibody is affinity-purified on mouse IgG3. By immunoblotting and ELISA this antibody reacts specifically with mouse IgG3. Cross-reactivity with mouse IgM, IgA, IgG1, IgG2a, IgG2b, IgG2c, and IgE is Antibody is affinity-purified on mouse IgM. By immunoblotting and ELISA this antibody reacts specifically with mouse IgM. Cross-reactivity with mouse IgG subclasses and IgA is negligible. This antibo Antibody is affinity-purified on rat IgA and conjugated to fluorescein isothiocyanate (FITC). Fluorophore:antibody ratio = 5.3. This antibody may cross-react with IgA of other species. Antibody is affinity-purified on rat IgG and conjugated fluorescein isothiocyanate (FITC). Fluorophore:antibody ratio = 5. This antibody may cross-react with IgG of other species. Antibody is affinity-purified on rat IgG1 and conjugated to fluorescein isothiocyanate. Fluorophore:antibody ratio = 5.1. This antibody may cross-react with IgG1 of other species. Antibody is affinity-purified on rat IgG2a and conjugated to fluorescein isothiocyanate (FITC). Fluorophore:antibody ratio = 5.6. This antibody may cross-react with IgG2a of other species. Antibody is affinity-purified on rat IgG2c and conjugated to fluorescein isothiocyanate. Fluorophore:antibody ratio = 6.2. This antibody may cross-react with IgG2c of other species. Antibody is affinity-purified on rat IgM and conjugated to fluorescein isothiocyanate (FITC). Fluorophore:antibody ratio = 7.7. This antibody may cross-react with IgM of other species. Antibody was affinity-purified on the peptide. This antibody does not recognize all N-terminal 6-His tagged proteins. By immunoelectrophoresis and ELISA this antibody reacts specifically with chicken IgY and with light chains common to other chicken immunoglobulins. Reactivity with other non-immunoglobulin serum pro By immunoelectrophoresis and ELISA this antibody reacts specifically with human IgA. Cross-reactivity with IgG, IgM and light chains is less than 0.1%. This antibody may cross-react with IgA of other By immunoelectrophoresis and ELISA this antibody reacts specifically with mouse IgG and with light chains common to other mouse immunoglobulins. Reactivity with non- immunoglobulin serum proteins is By immunoelectrophoresis and ELISA this antibody reacts specifically with mouse IgG- Fc. Cross-reactivity with IgA and IgM is negligible. This antibody may cross-react with IgG from other species. By immunoelectrophoresis and ELISA this antibody reacts specifically with rabbit IgG and with light chains common to other rabbit immunoglobulins. Reactivity with non- immunoglobulin serum proteins i By immunoelectrophoresis and ELISA this antibody reacts specifically with rabbit IgG- Fc. Reactivity with Fab fragments is not detected. This antibody may cross-react with IgG from other species. HSV I and II-infected cells. Human. In immunoblots a band of 85kDa is detected and may represent precursor. Lower mw bands are detected in some cell lines, including Jurkat, and may represent the processed mature protein. These antibodies recognize bovine and human rotavirus A. #20601 also reacts with monkey rotavirus (SA-11) and porcine rotavirus (PP). These antibodies recognize human GnRH. This antibody detects endogenous human estrogen receptor-alpha only when phosphorylated at serine 118.Accession no.: P03372, NP_000116.2 This antibody detects endogenous human estrogen receptor-alpha only when phosphorylated at serine 167.Accession no.: P03372, NP_000116.2 This antibody detects endogenous human HER2 only when phosphorylated at tyrosine 1221/1222.Accession no.: P04626, NP_001005862.1 This antibody detects endogenous human Myc only when phosphorylated at threonine 358. This antibody detects endogenous human progesterone receptor only when phosphorylated at serine 190.Accession no.: P06401, NP_000917.3 This antibody detects endogenous human Rel only when phosphorylated at serine 503. This antibody detects endogenous human, mouse, and rat Akt only when phosphorylated at threonine 308. This antibody detects endogenous human, mouse, and rat ATF2 only when phosphorylated at threonine 69 or 51. This antibody detects endogenous human, mouse, and rat Bcl-xL only when phosphorylated at serine 62.Accession no.: NP_612815.1 This antibody detects endogenous human, mouse, and rat c-Jun only when phosphorylated at serine 79. This antibody detects endogenous human, mouse, and rat Elk1 only when phosphorylated at threonine 417. This antibody detects endogenous human, mouse, and rat estrogen receptor-alpha only when phosphorylated at serine 106.Accession no.: P03372, NP_000116.2 This antibody detects endogenous human, mouse, and rat GATA1 only when phosphorylated at serine 310. This antibody detects endogenous human, mouse, and rat HER2 only when phosphorylated at tyrosine 877.Accession no.: P04626, NP_001005862.1 This antibody detects endogenous human, mouse, and rat MEF2a only when phosphorylated at threonine 312. This antibody detects endogenous human, mouse, and rat MEF2a only when phosphorylated at threonine 319. This antibody detects endogenous human, mouse, and rat NFkappaB-p100 only when phosphorylated at serine 866. This antibody detects endogenous human, mouse, and rat NFkappaB-p100 only when phosphorylated at serine 870. This antibody detects endogenous human, mouse, and rat NFkappaB-p105/p50 only when phosphorylated at serine 337. This antibody detects endogenous human, mouse, and rat NFkappaB-p65 only when phosphorylated at serine 468. This antibody detects endogenous human, mouse, and rat NFkappaB-p65 only when phosphorylated at threonine 435. This antibody detects endogenous human, mouse, and rat PKD/PKCu only when phosphorylated at serine 738.Accession no.: Q15139, NP_002733.2 This antibody detects endogenous human, mouse, and rat PTEN only when phosphorylated at serine 370.Accession no.: P60484, NP_000305.3 This antibody detects endogenous human, mouse, and rat PTEN only when phosphorylated at serine 380 and threonine 382/383.Accession no.: P60484, NP_000305.3 This antibody detects endogenous human, mouse, and rat PTEN only when phosphorylated at serine 380. This antibody detects endogenous human, mouse, and rat Raf1 only when phosphorylated at serine 259. This antibody detects endogenous human, mouse, and rat STAT3 only when phosphorylated at serine 727. This antibody detects endogenous human, mouse, rat, and monkey ATF2 only when phosphorylated at threonine 73 or 55. This antibody detects total endogenous human, mouse, and rat NFkappaB-p105. This antibody reacts with human metapneumovirus. The specific epitope has not been identified. This antibody recognizes Ab1-16 as well as other Ab peptides: Ab37, Ab38, Ab39, Ab40, and Ab42. NOTE: When administered to young Tg2576 mice with minimal Ab deposition and to older mice with higher A This antibody recognizes all human, mouse, and rat FLIP splice variants. This antibody recognizes alpha and b isoforms of human and mouse p53DINP1. This antibody recognizes an epitope at the C-terminus of human Bmf (Bcl-2-Modifying Factor), a novel BH3-only protein. In healthy cells, Bmf associates with the dynein light chain 2 component of the This antibody recognizes an epitope at the C-terminus of human CIKS/Act1 (Connection to IKK and SAPK/JNK), an activator of IKK. CIKS/Act1 interacts directly with IKKg and also activates activating tr This antibody recognizes an epitope at the C-terminus of human DC-SIGN, a dendritic cell receptor that can capture and transport HIV from mucosal areas to remote lymph nodes where HIV is then transfe This antibody recognizes an epitope at the C-terminus of human DUX4. It does not cross-react with DUX4c. This antibody recognizes an epitope at the C-terminus of human TCCR (T Cell Cytokine Receptor), a member of the type I cytokine receptor family. TCCR deficient mice have impaired responses of T helpe This antibody recognizes an epitope at the N-terminus of human CIKS/Act1 (Connection to IKK and SAPK/JNK), an activator of IKK. CIKS/Act1 interacts directly with IKKg and also activates activating tr This antibody recognizes an epitope at the N-terminus of human IL-21R, the receptor for IL-21. IL-21R complexes with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and This antibody recognizes an epitope at the N-terminus of human IL-22R, the receptor for IL-22. IL-22R complexes with IL-10 receptor b chain and mediates IL-22 signaling. IL-22 and its receptor activa This antibody recognizes an epitope at the N-terminus of human TCCR (T Cell Cytokine Receptor), a member of the type I cytokine receptor family. TCCR deficient mice have impaired responses of T helpe This antibody recognizes an epitope at the N-terminus of human, mouse, and rat Chk2 (Checkpoint Kinase 2). In response to DNA damage, ATM phosphorylates and activates Chk2 which in turn directly phos This antibody recognizes an epitope at the N-terminus of human, mouse, and rat p53R2. This antibody recognizes an epitope within Ab1-16 as well as other Ab peptides: Ab37, Ab38, Ab39, Ab40, and Ab42. NOTE: When administered to young Tg2576 mice with minimal Ab deposition and to older This antibody recognizes an epitope within the region of amino acids 439-458 of the cytoplasmic tail region of human CD4. This antibody recognizes full-length ARC (25 kD). This antibody recognizes full-length Bim (23kDa) of human, mouse, and rat. This antibody recognizes full-length DcR2 (34kDa). This antibody recognizes full-length human and mouse DR3 (59kDa). This antibody recognizes full-length human and mouse DR5 (57kDa). This antibody recognizes full-length human caspase-10 (59kDa). Since the sequences at C- termini of FLICE2 and Mch4 are different, this antibody recognizes only the FLICE2 form of caspase-10. This antibody recognizes full-length human caspase-9 (46kDa). This antibody recognizes full-length human CXCR4 (40 kD). This antibody recognizes full-length human DR3 (59kDa). This antibody recognizes full-length human DR4 (57kDa). This antibody recognizes full-length human IRAK (80 kD). This antibody recognizes full-length human IRAK2 (65 kD). This antibody recognizes full-length human RAIDD (22kDa). This antibody recognizes full-length human, monkey, and mouse Daxx (120kDa). This antibody recognizes full-length human, mouse, and rat FLIPalpha (55kDa). This antibody recognizes full-length human, mouse, and rat RICK (60kDa). This antibody recognizes full-length human, mouse, and rat ZIP kinase (52kDa). This antibody recognizes full-length mouse and human Apaf1 (115-130kDa). This antibody recognizes full-length mouse CAD (40kDa). This antibody recognizes full-length STAT1alpha (91 kD) and does not react with STAT1b. This antibody recognizes human AIF (67 kDa). This antibody recognizes human and mouse Acinus (220 kD). This antibody recognizes human and mouse BACE (approx. 70 kD). This antibody recognizes human and mouse Caspase-4 (36kDa). This antibody recognizes human and mouse ch-TOG. A BLAST search demonstrated 100% identity to the peptide immunogen in human, mouse, rat, chimpanzee, dog, cow, chicken, opossum, and frog. This antibody recognizes human and mouse CXCR4 (40 kD). This antibody recognizes human and mouse FLASH (220kDa). This antibody recognizes human and mouse MADD (200-220 kD). This antibody recognizes human and mouse MTBP which is involved in the p53 network of tumor suppression. p53 transcriptionally activates the MDM2 gene, then the translated MDM2 protein binds to p53 a This antibody recognizes human and mouse MyD88 (35 kD). This antibody recognizes human and mouse PHAP I (32kDa). The sequence of rat PHAP I is identical to human PHAP I. This antibody recognizes human and mouse PUMA (23kDa). A lower molecular weight band at 16kDa is detected in MOLT4 and U937 cell lysates and probably represents the PUMA-β protein. This antibody recognizes human ARTS (Apoptosis Related Protein in image Signaling Pathway), a novel mito-chondrial septin-like protein. ARTS translocates to the cell nucleus when apoptosis occurs. It This antibody recognizes human ASK1 (155kDa). This antibody recognizes human Bcl10 (31kDa). This antibody recognizes human BCMA (B Cell Maturation Protein). BCMA is a receptor for BAFF and April, two novel members of the TNF superfamily of proteins regulating immune response and the inducti This antibody recognizes human Bonzo (40 kD). This antibody recognizes human CCR5 (40 kD). This antibody recognizes human CIDE-A (23kDA) and does not cross-react with CIDE-B. This antibody recognizes human DFF40 (40kDa). This antibody recognizes human DR4 (57kDa). This antibody recognizes human DRAK1 (50kDa). No cross-reactivity with DRAK2, DAP or ZIP kinases. This antibody recognizes human DUX4. It does not cross-react with DUX4c. This antibody recognizes human FLIPγ (35kDa) and FLIPδ(25kDa) but not FLIPα or FLIPβ. This antibody recognizes human FPR1 at aa 305-GQDFRERLI-313 at the amino- terminal portion of the carboxyl-terminal tail. It also recognizes the same epitope in FPR2. This antibody recognizes human FPR1 at the cytoplasmic C-terminal aa 338- STLPSAEVELQAK-350. It is sensitive to C-terminal tail phosphorylation. It does not recognize human FPR2. This antibody recognizes human IKKalpha (85 kD). No cross-reactivity with IKKb or IKKg. This antibody recognizes human IKKalpha (85 kD). No cross-reactivity with IKKb or IKKg.<h5 This antibody recognizes human IKKb (87 kD). No cross-reactivity with IKKalpha or IKKg. This antibody recognizes human IKKepsilon (80 kD). No cross-reactivity with IKKalpha, IKKb or IKKg. This antibody recognizes human IL- 21R, the receptor for IL-21. IL-21R complexes with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate the JAK-S This antibody recognizes human IRAK2 (65 kD). No cross-reactivity with IRAK. This antibody recognizes human Livin (33kDa). This antibody recognizes human NIK. This antibody recognizes human otoferlin. This antibody recognizes human p62dok (62kD). This antibody recognizes human RAIDD (22kDa). This antibody recognizes human Survivin (17kDa). This antibody recognizes human TRAIL. This antibody recognizes human, mouse and rat CX3CR1 (50 kD). This antibody recognizes human, mouse and rat PHAP I (32kDa) and PHAP III (35kDa). This antibody recognizes human, mouse and rat PHAP I (32kDa), and does not cross-react with PHAP I2a or PHAP III. This antibody recognizes human, mouse and rat PHAP III (35kDa). This antibody recognizes human, mouse, and rat APP and the C99 fragment. This antibody recognizes human, mouse, and rat BAFF (approx. 38kDa). This antibody recognizes human, mouse, and rat BAFF-R. This antibody recognizes human, mouse, and rat Bassoon. Multiple isoforms are detected. This antibody recognizes human, mouse, and rat caspase-12 (approx. 53kDa). This antibody recognizes human, mouse, and rat Caspase-8 (18kDa). This antibody recognizes human, mouse, and rat DcR1 (65kDa). This antibody recognizes human, mouse, and rat DEDAF (32kDa). This antibody recognizes human, mouse, and rat DFF40/CAD (40kDa). This antibody recognizes human, mouse, and rat EndoG (Endonuclease G) an enzyme that is activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase This antibody recognizes human, mouse, and rat F1A (70kDa). This antibody recognizes human, mouse, and rat GFRalpha-1 (approx. 50 kD). This antibody recognizes human, mouse, and rat GFRalpha-3 (approx. 43 kD). This antibody recognizes human, mouse, and rat IKKg (52 kD). No cross-reactivity with IKKalpha, IKKb or IKKepsilon. This antibody recognizes human, mouse, and rat IL-1RAcP (66 kD). No cross-reactivity with other members of the IL-1 receptor family. This antibody recognizes human, mouse, and rat ILP-2 (33kDa). This antibody recognizes human, mouse, and rat IRAK-M (68 kD). No cross-reactivity with IRAK or IRAK2. This antibody recognizes human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetyl This antibody recognizes human, mouse, and rat RICK (60kDa). This antibody recognizes human, mouse, and rat Smac (25kDa). This antibody recognizes human, mouse, and rat SODD (60kDa). This antibody recognizes human, mouse, and rat TACE, and 80-130kDa bands are detected in immunoblots. These bands may represent mature protein, precursor, and glycosylated TACE. This antibody recognizes human, neurturin (14 kD). This antibody recognizes monomeric human and mouse Bnip3L. A band of 40kDa is detected in immunoblots. This antibody recognizes mouse and rat RIP3 (57kDa). This antibody recognizes mouse CIDE-A (25kDa) and does not cross-react with CIDE-B. This antibody recognizes native and recombinant human and mouse glypican-1. This antibody recognizes non-cleaved (45kDa) and cleaved DFF45. This antibody recognizes non-cleaved (45kDa) and cleaved mouse ICAD. This antibody recognizes rabies virus glycoprotein (UniProtKB Q08089) and neutralizes the following strains of rabies virus: CVS, Flury Lep, Flury HEP, Mokola 1, Mokola 2, Lagos bat, Duvenhage, and f This antibody recognizes RSV subtype A. This antibody recognizes ski protein of human, mouse, rat, chicken, and Xenopus. This antibody recognizes the fiber knob protein of human adenovirus 3. The fiber knob is involved in the initial interaction of adenovirus with cellular membrane receptors. This antibody recognizes the monomeric (9 kD) and dimeric (18 kD) forms of human eotaxin This antibody recognizes the proenzyme of human DNase II (40kDa). This antibody specifically reacts with human E-Cadherin, but does not react with rat E-Cadherin. This antibody inhibits E-Cadherin dependent cell-cell contact. This antibody specifically recognizes an epitope within Abx-40. NOTE: When administered to young Tg2576 mice with minimal Ab deposition, this antibody reduced Ab accumulation in the brain. This antibody specifically recognizes an epitope within Abx-42. NOTE: When administered to young Tg2576 mice with minimal Ab deposition, this antibody reduced Ab accumulation in the brain. This antibody specifically recognizes human IRAK-4 (IL-1 Receptor Associated Kinase-4). This antibody does not cross-react with other IRAKs. This antibody recognizes the post 3'-UGA codon region of human CD4.
