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Anti-Neisseria gonorrhoeae Mouse Monoclonal Antibody – Library Pack (158101)

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 4 x 100ug ELISA Neisseria Gonorrhoeae
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Overview
Product Name Anti-Neisseria gonorrhoeae Mouse Monoclonal Antibody - Library Pack (158101)
Description Anti-Neisseria gonorrhoeae Mouse Monoclonal Antibody Library Pack - Includes 100 ug of each of the following antibodies:

15801 - Anti-Neisseria gonorrhoeae Mouse Monoclonal Antibody - Clone GC12-316.4 - Isotype IgG3

15802 - Anti-Neisseria gonorrhoeae Mouse Monoclonal Antibody - Clone GC12-323.6 - Isotype IgG1

15803 - Anti-Neisseria gonorrhoeae Mouse Monoclonal Antibody - Clone GC12-351.2 - Isotype IgG1

15804 - Anti-Neisseria gonorrhoeae Mouse Monoclonal Antibody - Clone GC12-351.4 - Isotype IgG1

Target Neisseria gonorrhoeae
Species Reactivity Neisseria Gonorrhoeae
Applications ELISA
Host Mouse
Clonality Monoclonal
Immunogen Pool of UV-inactivated Neisseria gonorrhoeae cells: Neisseria Reference laboratory strains G-7, R-11, and 7122 (W-I), 5766 and 8038 (W-II), and 8660 (W-III).
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Specificity Information
Specificity These antibodies recognize N. gonorrhoeae. They do not cross-react with N. meningitides, N. cinerea, N. lactamica, N. sicca, B. catarrhalis, E. coli, Proteus mirabilis, Gardnerella vaginalis, Group B Strep. or Chlamydia trachomatis.
Target ID Neisseria gonorrhoeae
Research Areas Infectious Disease
Background Neisseria gonorrhoeae is a gram-negative coccus and is the cause of the sexually transmitted disease gonorrhea with humans as its only natural host. Although it does not produce any exotoxins, Neisseria gonorrhoeae has a wide range of virulence determinants. The first stages of infection, which include adherence and invasion, are mediated by surface components; N. gonorrhoeae first attaches to epithelial cells by means of its fimbriae. After initial attachment, the bacteria enter a second stage of binding mediated by the outer membrane protein P.II (also known as Opa) which is needed for tight binding and invasion of epithelial cells. P.II from one bacterium will bind to lipooligosaccharide of an adjacent bacterium, which allows for the construction of a small colony that may function similarly to a biofilm. Neisseria gonorrhoeae also produces an IgA1 protease that may take part in the colonization stage.
Application Images
Additional Information
Handling
Storage These antibodies are stable for at least one (1) year at -20° to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions These antibodies have been qualified for use in ELISA to detect N. gonorrhoeae.

End users should determine optimal concentrations for their applications.
References & Data Sheet